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Cannabis Plant

Understanding Chemotype Essential Oils: A Cannabis Formulator’s Perspective

If you formulate cannabis products, you already understand how two plants from the same strain can produce dramatically different therapeutic properties. That same principle drives chemotype classification in essential oils. Much like cannabis, plants act as natural chemists, shaping their chemical expression through environment and genetics—concepts explored further in our guide on how plants function as natural chemists.
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Farmers hold marijuana (cannabis) trees on their farms.

Phytochemistry of Cannabis: Unlocking Terpene Profiles

When you experience cannabis, you're encountering far more than Tetrahydrocannabinol (THC) and Cannabidiol (CBD). The aroma profile that defines each strain comes from terpenes—volatile compounds that shape both sensory experience and physiological effects. Research reveals these phytochemicals activate CB1 receptors at 10–50% of THC's activity, influencing neurotransmitter interactions without causing intoxication on their own.
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Close up of green canabis plant

Fungal metabolites in cannabis: biosynthesis and benefits

When most people think about cannabis chemistry, cannabinoids and terpenes dominate the conversation. But emerging research reveals a fascinating hidden layer: fungal metabolites. These bioactive compounds, produced by endophytic fungi living symbiotically within cannabis plants, represent an unexplored dimension of plant chemistry and expand how we understand plants as natural chemists.
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Plants Chemical Expression

Flavonoid synthesis in cannabis: unlocking cultivar-specific effects

While cannabinoids dominate cannabis research, flavonoids quietly shape the cultivar-specific effects consumers experience. These secondary metabolites, derived from flavone with powerful antioxidant properties and formed through plant metabolite formation, represent over 10,000 identified molecules across plant biology. In cannabis, unique compounds like cannflavins deliver anti-inflammatory effects up to 30 times more potent than aspirin.
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Ribbon diagram of glycosidase with an arrow showing the cleavage of the maltose sugar substrate into two glucose products.

The Role of Enzymes in Plant Metabolite Formation

Plants are master chemists. Behind their foliage and blossoms, countless molecular factories are at work. The secret agents of these factories? Enzymes. Without enzymes directing traffic, routing building blocks, and setting pathways in motion, plants couldn’t build the wide range of compounds that define their flavor, fragrance, color, defense and ecological interaction. In this blog, […]
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